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INHALATIONAL ANESTHETICS (QUESTIONS)

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  1.  1. All of the following factors decrease the minimum alveolar concentration (MAC) of an inhalational anaesthetic agent except: 
  2. 2. The potency of an inhalational anesthetic depends on:
  3. 3.Exception of Meyer-Overton rule are A/E:
  4. 4. Least soluble anesthetic agent is:
  5. 5. Least blood gas partition coefficient anesthetic agent:
  6. 6. Fastest acting agent :
  7. 7. Least diffusion coefficient is for :
  8. 8. Which one of the following is the fastest acting inhalational agent:
  9. 9. Pungent volatile anesthetic agents are:
  10. 10. Which of the following inhalational agents has the minimum blood gas solubility coefficient:
  11. 11. Which of the following is not true about xenon anesthesia ?
  12. 12. True about xenon anesthesia:
  13. 13. True about nitric oxide
  14. 14. True about inhaled nitric oxide:
  15. 15. Which of the following inhaled gas is used to decrease
  16. pulmonary artery pressure in adults and infants:
  17. 16. At the end of anesthesia after discontinuation of nitrous oxide and removal of endotracheal tube, 100% oxygen is administered to the patient to prevent:
  18. 17. Use of nitrous oxide is contraindicated in all of the following surgeries except:
  19. 18. All of the following are the disadvantages of anesthetic ether, except:
  20. 19. True about halothane
  21. 20. True about halothane:
  22. 21. Which of the following are contraindication for halothane use:
  23. 22. All are true except
  24. 23. Which of the following fluorinated anesthetics corrodes metal in vaporizers and breathing systems:
  25. 24. Which of the following inhalational agent is contraindicated in a patient with history of epilepsy:
  26. 25. Least cardiotoxic anesthetic agent:
  27. 26. Which of the following statements regarding desflurane is correct:
  28. 27. A seventy year old patient is posted for a surgery which is likely to last 4-6 hours. The best inhalational agent of choice for maintenance of anesthesia in such a case is:
  29. 28. Rapid induction of anesthesia occurs with which of the following inhalational anesthetics:
  30. 29. Which of the following is an epileptogenic anesthetic agent:
  31. 30. A six-year-old child is posted for elective urology surgery under general anesthesia. He refuses to allow the anaesthesiologist an I.V. access. The best inhalational agentof choice for induction of anesthesia is:
  32. 31. Which is contraindicated in closed system anesthesiology:
  33. 32. True about Sevoflurane:
  34. 33. NOT TRUE regarding sevoflurane:
  35. 34. Which of following is/are false: 
  36. 35. Risk of halothane toxicity in hepatic failure is increased in all EXCEPT
  37. 36. Which among the following is an anesthetic gas
  38. 37. The anesthetic agent that is contraindicated in the presence of jaundice:
  39. 38. The anesthetic agent that causes maximum increase in intracranial pressure is:
  40.  39. The anesthetic agent that expands the air filled cavities in the body is:
  41. 40. Which anesthetic is not used in pneumothorax:
  42. 41. Bronchospasm is caused by all except:
  43. 42. “MAC”of desflurane is:
  44. 43. Which of the following should be considered as the cause of generalized convulsions 20 minutes postoperatively:
  45. 44. In which plane of anesthesia, movement of eyeball is lost:
  46. 45. An anesthetic agent with boiling temperature more than 75°C is:          
  47. 46. All of the following anesthetic agents have been consistently shown to better preserve hepatic blood flow and oxygenation except:
  48. 47. Action of scoline is potentiated by all except:
  49. 48. Which of the following inhalational anesthetics should be avoided in middle ear surgery:
  50. 49. Which one of the following is the fastest acting inhalational agent:
  51. 50. Inhalational agent which is a good uterine relaxant:
  52. 51. Gas stored in liquid form is:
  53. 52. Ether was first used by:
  54. 53. Anesthesia of choice for induction in children is:
  55. 54. Bone marrow depression occurs with:
  56. 55. One of the following inhalational volatile anesethetic agent is not a fluorinated hydrocarbon:
  57. 56. In the context of inhalational anesthetics, MAC refers to:
  58. 57. Diffusion into gas-containing spaces is a problem with:
  59. 58. All the undermentioned are true with respect to ether anesthesia except:
  60. 59. MAC of sevoflurane in % is:
  61. 60. All are true regarding desflurane except:
  62. 61. High output renal failure may be caused by:
  63. 62. True about N2O
  64. 63. Inhalational agent of choice in children:
  65. ANSWERS:

 1. All of the following factors decrease the minimum alveolar concentration (MAC) of an inhalational anaesthetic agent except: 

a. Hypothermia

b. Hyponatremia

c. Hypocalcemia

d. Anemia

2. The potency of an inhalational anesthetic depends on:

a. Blood gas partition coefficient

b. Oil-gas partition coefficient

c. Gas pressure

d. Blood pressure

3.Exception of Meyer-Overton rule are A/E:

a. Non anaesthetics

b. Non immobilizer

c. Cut off effect

d. Hydrophobic site of action

4. Least soluble anesthetic agent is:

a. Desflurane

b. Sevoflurane

c. Halothane

d. Methoxyflurane

5. Least blood gas partition coefficient anesthetic agent:

a. Desflurane

b. Nitrous oxide

c. Halothane

d. Ether

6. Fastest acting agent :

a. Sevoflurane

b. Desflurane

c. Isoflurane

d. None

7. Least diffusion coefficient is for :

a. Isoflurane

b. Enflurane

c. Halothane

d. N2O

8. Which one of the following is the fastest acting inhalational agent:

a. Halothane

b. Isoflurane

c. Ether

d. Sevoflurane

9. Pungent volatile anesthetic agents are:

a. Halothane

b. Isoflurane

c. Sevoflurane

d. Desflurane

e. Nitrous oxide

10. Which of the following inhalational agents has the
minimum blood gas solubility coefficient:

a. Isoflurane

b. Sevoflurane

c. Desflurane

d. Nitrous oxide

11. Which of the following is not true about xenon anesthesia ?

a. Non explosive

b. Minimal cardiovascular side effects

c. Slow induction and slow recovery

d. Inhibits Ca++ pump and low blood gas solubility

12. True about xenon anesthesia:

a. Rapid induction and recovery

b. Low potency

c. High blood solubility

d. Non-explosive

e. Heavier than air

13. True about nitric oxide

a. Formed from L-arginine by NO synthase

b. Causes vasodilation in all vessels

c. Used in portal hypertension

d. Interacts with Hb

e. Used in erectile dysfunction

14. True about inhaled nitric oxide:

a. Causes generalized (systemic) vasodilation

b. Dilates pulmonary arteries

c. Causes hypotension and increase in pulmonary arterial pressure

d. Least systemic effects

e. Better (improves) ventilation perfusion match

15. Which of the following inhaled gas is used to decrease

pulmonary artery pressure in adults and infants:

 a. Nitrous oxide

b. Nitrogen dioxide

c. Nitric oxide

d. Nitrogen

16. At the end of anesthesia after discontinuation of nitrous oxide and removal of endotracheal tube, 100% oxygen is administered to the patient to prevent:

a. Diffusion hypoxia

b. Second gas effect

c. Hyperoxia

d. Bronchospasm

17. Use of nitrous oxide is contraindicated in all of the following surgeries except:

a. Cochlear implant

b. Microlaryngeal surgery

c. Vitrioretinal surgery

d. Exentration operation

18. All of the following are the disadvantages of anesthetic ether, except:

a. Induction is slow

b. Irritant nature of ether increases salivary and bronchial

secretions

c. Cautery cannot be used. 

d. Affects blood pressure and is liable to produce

arrhythmias.

19. True about halothane

a. 1% thymol is used as preservative

b. It sensitizes heart to catecholamines at 1 MAC

c. 20% metabolized

d. It is not usually given in same patient within 3 months

e. It forms compound -A with sodalime

20. True about halothane:

a. Causes bronchodilation

b. Antiarrhythmic

c. Can be used in hepatitis

d. Uterine contraction occurs

e. Causes hepatitis

21. Which of the following are contraindication for halothane use:

a. Male sex

b. Middle age

c. Recent halothane use

d. Associated liver pathology

e. Obesity

22. All are true except

a. Halothane is good analgesic agent

b. Halothane sensitizes heart to catecholamines

c. Halothane relaxes bronchi

d. Halothane causes hepatitis and liver cell necrosis

23. Which of the following fluorinated anesthetics corrodes metal in vaporizers and breathing systems:

a. Sevoflurane

b. Enflurane

c. Isoflurane

d. Halothane

24. Which of the following inhalational agent is contraindicated in a patient with history of epilepsy:

a. Isoflurance

b. Enflurane

c. Halothane

d. Sevoflurane

25. Least cardiotoxic anesthetic agent:

a. Enflurane

b. Isoflurane

c. Sevoflurane

d. Halothane, trilene, ketamine

26. Which of the following statements regarding desflurane is correct:

a. It causes severe myocardial depression

b. It is a structural analogue of isoflurane

c. It has very high blood and tissue gas partition coefficients

d. It is metabolically unstable

27. A seventy year old patient is posted for a surgery which is likely to last 4-6 hours. The best inhalational agent of choice for maintenance of anesthesia in such a case is:

a. Methoxyflurane

b. Ether

c. Trichlorethylene

d. Desflurane

28. Rapid induction of anesthesia occurs with which of the following inhalational anesthetics:

a. Isoflurane

b. Halothane

c. Desflurane

d. Sevoflurane

29. Which of the following is an epileptogenic anesthetic
agent:

a. Isoflurane

b. Sevoflurane

c. Methoxyflurane

d. Halothane

30. A six-year-old child is posted for elective urology surgery under general anesthesia. He refuses to allow the anaesthesiologist an I.V. access. The best inhalational agentof choice for induction of anesthesia is:

a. Sevoflurane

b. Methoxyflurane

c. Desflurane

d. Isoflurane

31. Which is contraindicated in closed system anesthesiology:

a. Methoxyflurane

b. Isoflurane

c. Sevoflurane

d. Desflurane

32. True about Sevoflurane:

a. Isopropyl ether

b. MAC is 2%

c. Good to use in old age

d. Blood gas partition coefficient is more than halothane

e. Formation of compound A with baralyme

33. NOT TRUE regarding sevoflurane:

a. MAC is higher than isoflurane

b. Blood gas coefficient is higher than desflurane

c. More cardio depressant than isoflurane

d. Sevoflurane is less cardio depressant than isoflurane

34. Which of following is/are false: 

a. Enflurane interacts with soda lime

b. Sevoflurane causes seizures

c. Rapid recovery from propofol

d. Ketamine acts through GABA receptors

e. MAC indicates potency of inhalational agents

35. Risk of halothane toxicity in hepatic failure is increased in all EXCEPT

a. Pregnancy

b. Previous halothane use

c. Male sex

d. None

36. Which among the following is an anesthetic gas

a. N2O + O2

b. Helium + O2

c. N2O + Helium

d. None

37. The anesthetic agent that is contraindicated in the presence of jaundice:

a. Halothane

b. Ether

c. Gallamine

d. Nitrous oxide

38. The anesthetic agent that causes maximum increase in intracranial pressure is:

a. Isoflurane

b. Halothane

c. Enflurane

d. Desflurane

 39. The anesthetic agent that expands the air filled cavities in the body is:

a. Halothane

b. Ether

c. Sevoflurane

d. Nitrous oxide

40. Which anesthetic is not used in pneumothorax:

a. N2O

b. Halothane

c. Enflurane

d. Desflurane

41. Bronchospasm is caused by all except:

a. Morphine

b. Halothane

c. Propofol

d. Nitrous oxide

42. “MAC”of desflurane is:

a. 1.15

b. 2

c. 4

d. 6

43. Which of the following should be considered as the cause of generalized convulsions 20 minutes postoperatively:

a. Halothane

b. Enflurane

c. Isoflurane

d. Sevoflurane

44. In which plane of anesthesia, movement of eyeball is lost:

a. Stage 3 plane 1

b. Stage 1 plane 3

c. Stage 2 plane 3

d. Stage 4

45. An anesthetic agent with boiling temperature more than 75°C is:          

a. Ether

b. Halothane

c. Cyclopropane

d. Methoxyflurane

46. All of the following anesthetic agents have been
consistently shown to better preserve hepatic blood flow
and oxygenation except:

a. Sevoflurane

b. Desflurane

c. Isoflurane

d. Enflurane Ref

47. Action of scoline is potentiated by all except:

a. Nitrous oxide

b. Sevoflurane

c. Isoflurane

d. Halothane

48. Which of the following inhalational anesthetics should be avoided in middle ear surgery:

a. Halothane

b. Nitrous oxide

c. Ether

d. Isoflurane

49. Which one of the following is the fastest acting inhalational agent:

a. Halothane

b. Isoflurane

c. Ether

d. Sevoflurane

50. Inhalational agent which is a good uterine relaxant:

a. Halothane

b. Isoflurane

c. Sevoflurane

d. Desflurane

51. Gas stored in liquid form is:

a. Carbon dioxide

b. Nitrous oxide

c. Cyclopropane

d. Oxygen

52. Ether was first used by:

a. Preistly

b. Morton

c. Wells

d. Simpson

53. Anesthesia of choice for induction in children is:

a. Procaine

b. Desflurane

c. Sevoflurane

d. Ropivacaine

54. Bone marrow depression occurs with:

a. Cocaine

b. Lignocaine

c. N2O

d. Bupivacaine

55. One of the following inhalational volatile anesethetic agent is not a fluorinated hydrocarbon:

a. Halothane

b. Isoflurane

c. Diethyl ether

d. Sevoflurane

56. In the context of inhalational anesthetics, MAC refers to:

a. Maximum anesthetic concentration

b. Minimum anesthetic concentration

c. Minimum alveolar concentration

d. Maximum alveolar concentration

57. Diffusion into gas-containing spaces is a problem with:

a. Halothane

b. Nitrous oxide

c. Isoflurane

d. Ether

58. All the undermentioned are true with respect to ether
anesthesia except:

a. It is flammable

b. Use of ether is associated with quick induction time

c. There will be a delayed emergence’ from anesthesia

d. Use of the ether is associated with a high incidence of nausea and vomiting

59. MAC of sevoflurane in % is:

a. 0.75

b. 0.42

c. 1.15

d. 2

60. All are true regarding desflurane except:

a. Low blood / gas partition coefficient

b. Minimum alveolar concentration range from 5–7%

c. Sweet smelling agent

d. Suitable for day care surgery

61. High output renal failure may be caused by:

a. Methoxyflurane

b. Diethyl ether

c. Enflurane

d. Halothane

62. True about N2O

a. Pin index 3,5

b. Cylinder is blue in color

c. Stored as liquid

d. MAC 105

63. Inhalational agent of choice in children:

a. Sevoflurane

b. Isofurane

c. Desflurane

d. Halothane

e. N2O

ANSWERS:

1. c. Hypocalcemia        2. b. Oil-gas partition     3. d. Hydrophobic site   4. a. Desflurane

5. a. Desflurane             6. b. Desflurane             7. d. N2O                      8. d. Sevoflurane

9. b and d                      10. c. Desflurane           11. c. Slow induction     12. a, b, d and e

13. a, b and d                14. b, d and e                15. c. Nitric oxide        16. a. Diffusion hypoxia 

17. d. Exentration          18. d. Affects blood       19. a, b and c                20. a and e

21. c and d                    22. a. Halothane            23. d. Halothane           24. b. Enflurane 

25. b. Isoflurane            26. b. It is a structural    27. d. Desflurane         28. c. Desflurane 

29. b. Sevoflurane        30. a. Sevoflurane         31. c. Sevoflurane        32. a, b, c and e 

33. d. Sevoflurane        34. a, b and d                35. d. Male sex            36. a. N2O + O2

37. a. Halothane          38. b. Halothane            39. d. Nitrous oxide     40. a. N2O 

41. b. Halothane          42. d. 6                          43. b. Enflurane          44. a. Stage 3 plane 1 

45. d. Methoxyflurane  46. d. Enflurane            47. a. Nitrous oxide      48. b. Nitrous oxide

49. d. Sevoflurane       50. a. Halothane           51. b. Nitrous oxide      52. b. Morton 

53. c. Sevoflurane       54. c. N2O                    55. c. Diethyl ether      56. c. Minimum alveolar

57. b. Nitrous oxide     58. b. Use of ether is     59. d. 2                       60. c. Sweet smelling

61. a. Methoxyflurane  62. a, b, c and d           63. a. Sevoflurane


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